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CS-W001157 4
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5-Aminobenzene-1,3-diol hydrochloride

  • CAS No. 6318-56-5

  • Cat. No. CS-W005966
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Aminobenzene-1,3-diol hydrochloride|CS-W005966

Structure of 6318-56-5

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General Information

  • CAS No. 6318-56-5
  • Cat. No. CS-W005966
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClNO₂
  • Molecular Weight 161.59
  • Synonym(s) 5-aMinoresorcinolhcl
  • SMILES NC1=CC(O)=CC(O)=C1.Cl

Description

5-Aminobenzene-1,3-diol hydrochloride delivers a bench-stable, moisture-tolerant platform for constructing bioactive scaffolds. The compound features an electron-rich aromatic core flanked by strategically positioned amine and phenolic groups, enabling direct coupling in peptide synthesis and conjugation workflows. This hydrochloride salt enhances solubility in polar solvents while maintaining stability under standard handling conditions.

Application

5-Aminobenzene-1,3-diol hydrochloride serves as a versatile building block for the synthesis of heterocyclic scaffolds and functionalized aromatic systems. Its ortho-dihydroxy and amino functionalities enable efficient coupling reactions, metal coordination, and derivatization under mild conditions. The hydrochloride salt enhances bench stability and solubility in polar solvents, facilitating purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • null|null
      108-73-6
    • ~67%
    • In-stock
      5-Aminobenzene-1,3-diol hydrochloride|CS-W005966
      6318-56-5

    References

    • National University Corporation Shizuoka University; Nissan Chemical Industries, Ltd.; YAMANAKA, Masamichi; HIGASHI, Daisuke Patent: EP2684868 A1, 2014 ; Location in patent: Paragraph 0159; 0160; 0161 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   1.1018
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   0

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