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CS-W001157 4
Total: USD 88.00

Potassium trimethoxy(trifluoromethyl)borate

  • CAS No. 626232-27-7

  • Cat. No. CS-0312505
  • Molecule weight212.02
  • Purity≥97%
  • MDL No.MFCD22124929

*For research and further manufacturing use only, not for direct human use.

Potassium trimethoxy(trifluoromethyl)borate|CS-0312505

Structure of 626232-27-7

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General Information

  • CAS No. 626232-27-7
  • Cat. No. CS-0312505
  • Purity ≥97%
  • MDL No. MFCD22124929
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉BF₃KO₃
  • Molecular Weight 212.02
  • Synonym(s) Potassium (Trifluoromethyl)trimethoxyborate
  • SMILES F[C-](F)([B+3]([O-]C)([O-]C)[O-]C)F.[K+]

Description

Potassium trimethoxy(trifluoromethyl)borate delivers a stable, moisture-tolerant boron source featuring a trifluoromethyl group and three methoxy substituents. This reagent integrates efficiently into cross-coupling reactions, enabling direct functionalization of aryl and heteroaryl halides with high chemoselectivity under mild conditions.

Application

Potassium trimethoxy(trifluoromethyl)borate serves as a stable, bench-ready source of the trifluoromethylboronate group, enabling efficient Suzuki-Miyaura cross-coupling reactions under mild conditions. Its high functional group tolerance and compatibility with diverse aryl and vinyl electrophiles make it a practical reagent for constructing C–CF₃ bonds in pharmaceutical and agrochemical synthesis. The trimethoxyborane moiety enhances solubility and stability, facilitating straightforward purification and reproducible reaction outcomes in industrial-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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