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CS-W001157 4
Total: USD 88.00

4-Chloro-7-fluoro-6-nitroquinazoline

  • CAS No. 162012-70-6

  • Cat. No. CS-0000035
  • Purity≥98%
  • MDL No.MFCD08063159

*For research and further manufacturing use only, not for direct human use.

4-Chloro-7-fluoro-6-nitroquinazoline|CS-0000035

Structure of 162012-70-6

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General Information

  • CAS No. 162012-70-6
  • Cat. No. CS-0000035
  • Purity ≥98%
  • MDL No. MFCD08063159
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₃ClFN₃O₂
  • Molecular Weight 227.58
  • Synonym(s) quinazoline, 4-chloro-7-fluoro-6-nitro-
  • SMILES ClC(C1=C2)=NC=NC1=CC(F)=C2[N+]([O-])=O

Synthesis

  • Route1

    References

    • Barth, Hubert; Bridges, Alexander James; Heemstra, Ronald J.; Horne, Nicole Marcia; Hughes, Robert Craig; Jacks, Thomas Elliott; McNamara, Dennis Joseph; Schneider, Simon; Steiner, Klaus; Toogood, Peter Laurence; Winters, Roy Thomas Patent: US2004/158065 A1, 2004 ; Location in patent: Page 18 ;
  • Route2
    • 2-Amino-4-fluorobenzoic acid Afatinib Impurity|CS-0167288
      446-32-2
    • ~%
    • In-stock
      4-Chloro-7-fluoro-6-nitroquinazoline|CS-0000035
      162012-70-6

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 4 p. 918 - 928
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 4 p. 918 - 928

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   68.92
  • LogP   2.3305
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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