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CS-W001157 4
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tert-Butyl 4-(5-bromothiazol-2-yl)piperazine-1-carboxylate

  • CAS No. 623588-36-3

  • Cat. No. CS-0145322
  • Molecule weight348.26
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(5-bromothiazol-2-yl)piperazine-1-carboxylate|CS-0145322

Structure of 623588-36-3

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General Information

  • CAS No. 623588-36-3
  • Cat. No. CS-0145322
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈BrN₃O₂S
  • Molecular Weight 348.26
  • Synonym(s) Tert-butyl 4-(5-bromo-1,3-thiazol-2-yl)piperazine-1-carboxylate
  • SMILES O=C(N1CCN(C2=NC=C(Br)S2)CC1)OC(C)(C)C

Synthesis

  • Route1
    • Tert-butyl 4-(thiazol-2-yl)piperazine-1-carboxylate|CS-0366474
      474417-23-7
    • ~93%
    • tert-Butyl 4-(5-bromothiazol-2-yl)piperazine-1-carboxylate|CS-0145322
      623588-36-3

    References

    • SCHERING CORPORATION Patent: WO2008/156739 A1, 2008 ; Location in patent: Page/Page column 216-217 ; WO 2008/156739 A1
  • Route2

    References

    • F. HOFFMANN-LA ROCHE AG Patent: WO2006/72436 A1, 2006 ; Location in patent: Page/Page column 36 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.67
  • LogP   2.9627
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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