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Structure of 209733-13-1
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This piperazinylthiazole derivative features a hydrochloride salt form that enhances solubility and stability in aqueous media. The electron-rich piperazine ring enables efficient coordination in metal-ligand systems, while the thiazole core provides a rigid, planar scaffold suitable for pharmaceutical scaffolding. This compound integrates readily into bioactive molecules requiring polar heterocyclic motifs with tunable basicity.
2-(Piperazin-1-yl)thiazole hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its piperazine moiety offers enhanced solubility and hydrogen-bonding capacity, while the hydrochloride salt ensures improved crystallinity and bench stability. The compound functions as a key intermediate in the synthesis of kinase inhibitors and other bioactive molecules, exhibiting robust compatibility with standard coupling and functionalization reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: