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CS-W001157 4
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Z-D-Dap-OH

  • CAS No. 62234-37-1

  • Cat. No. CS-0041646
  • Purity≥97%
  • MDL No.MFCD00237346

*For research and further manufacturing use only, not for direct human use.

Z-D-Dap-OH|CS-0041646

Structure of 62234-37-1

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General Information

  • CAS No. 62234-37-1
  • Cat. No. CS-0041646
  • Purity ≥97%
  • MDL No. MFCD00237346
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄N₂O₄
  • Molecular Weight 238.24
  • Synonym(s) N-Cbz-L-2,3-Diaminopropionic Acid; Z-D-Dap-OH
  • SMILES O=C(O)[C@H](NC(OCC1=CC=CC=C1)=O)CN

Description

Z-D-Dap-OH is a protected diaminopimelic acid derivative featuring a Z-configured double bond and a terminal hydroxyl group. This configuration enhances its utility in peptide synthesis, particularly for incorporating non-natural amino acids into cyclic or constrained scaffolds. The molecule exhibits improved solubility and stability under standard coupling conditions.

Synthesis

  • Route1

    References

    • Arnold; Kalantar; Vederas Journal of the American Chemical Society, 1985 , vol. 107, # 24 p. 7105 - 7109
  • Route2

    References

    • Helvetica Chimica Acta, , vol. 72, # 5 p. 1043 - 1051
  • Route3
    • null|null
      501-53-1
    • ~%
    • In-stock
      Z-D-Dap-OH|CS-0041646
      62234-37-1

    References

    • Tetrahedron Letters, , vol. 41, # 10 p. 1637 - 1641

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   0.3247
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   5

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