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Structure of 61761-32-8
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5-Fluoronaphthalen-1-ol features a naphthalene core with a hydroxyl group at position 1 and a fluorine substituent at position 5, delivering enhanced electron-withdrawal and improved metabolic stability. This combination enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring precise electronic tuning.
5-Fluoronaphthalen-1-ol serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the aromatic ring via palladium-catalyzed cross-coupling reactions. Its stability under standard bench conditions and compatibility with diverse reaction systems make it ideal for constructing complex polycyclic architectures. The fluorine substituent enhances metabolic stability and modulates electronic properties, supporting its use in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: