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Structure of 61442-38-4
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6-Aminopyrazine-2-carboxylic acid features a fused pyrazine core functionalized with amino and carboxylic acid groups at opposite positions, enabling dual-site conjugation. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and serves as a key intermediate in the synthesis of bioactive molecules.
6-Aminopyrazine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its dual functionality—amine and carboxylic acid groups—enables straightforward derivatization via amidation, esterification, or coupling reactions. The pyrazine core provides enhanced metabolic stability and favorable electronic properties in bioactive scaffolds. Bench-stable and readily purified by recrystallization, it functions effectively in standard peptide coupling and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: