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CS-W001157 4
Total: USD 88.00

Methyl 6-aminopyrazine-2-carboxylate

  • CAS No. 118853-60-4

  • Cat. No. CS-W003738
  • Purity≥98%
  • MDL No.MFCD10697802

*For research and further manufacturing use only, not for direct human use.

Methyl 6-aminopyrazine-2-carboxylate|CS-W003738

Structure of 118853-60-4

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General Information

  • CAS No. 118853-60-4
  • Cat. No. CS-W003738
  • Purity ≥98%
  • MDL No. MFCD10697802
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₃O₂
  • Molecular Weight 153.14
  • Synonym(s) Pyrazinecarboxylic acid, 6-amino-, methyl ester (9CI)
  • SMILES COC(=O)c1cncc(n1)N

Description

Methyl 6-aminopyrazine-2-carboxylate features a pyrazine core functionalized with an amino group at the 6-position and a methyl ester at the 2-position. This electron-deficient heterocycle integrates readily into synthetic scaffolds, offering enhanced solubility and stability under standard conditions. The amine moiety enables direct derivatization for medicinal chemistry applications.

Application

Methyl 6-aminopyrazine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazine-based heterocycles. The amino and ester functionalities offer orthogonal reactivity for late-stage functionalization, including amidation, acylation, and coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols facilitate straightforward purification and integration into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   -0.1546
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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