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CS-W001157 4
Total: USD 88.00

5,7-Dichloro-6-methylpyrazolo[1,5-a]pyrimidine

  • CAS No. 61098-38-2

  • Cat. No. CS-0570438
  • Molecule weight202.04
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,7-Dichloro-6-methylpyrazolo[1,5-a]pyrimidine|CS-0570438

Structure of 61098-38-2

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General Information

  • CAS No. 61098-38-2
  • Cat. No. CS-0570438
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅Cl₂N₃
  • Molecular Weight 202.04
  • Synonym(s) None
  • SMILES CC1=C(N2C(=CC=N2)N=C1Cl)Cl

Synthesis

  • Route1
    • null|null
      57489-71-1
    • null|null
      10025-87-3
    • ~81%
    • 5,7-Dichloro-6-methylpyrazolo[1,5-a]pyrimidine|CS-0570438
      61098-38-2

    References

    • CYLENE PHARMACEUTICALS INC.; HADDACH, Mustapha; RYCKMAN, David; RAFFAELE, Nicholas Patent: WO2011/31979 A1, 2011 ; Location in patent: Page/Page column 139 ; WO 2011/031979 A1
  • Route2
    • null|null
      57489-71-1
    • ~%
    • 5,7-Dichloro-6-methylpyrazolo[1,5-a]pyrimidine|CS-0570438
      61098-38-2

    References

    • ONO PHARMACEUTICAL CO., LTD. Patent: EP1666468 A1, 2006 ; Location in patent: Page/Page column 41 ; EP 1666468 A1
  • Route3

    References

    • Kosugi, Tomomi; Mitchell, Dale R.; Fujino, Aiko; Imai, Minoru; Kambe, Mika; Kobayashi, Shinji; Makino, Hiroaki; Matsueda, Yohei; Oue, Yasuhiro; Komatsu, Kanji; Imaizumi, Keiichiro; Sakai, Yuri; Sugiura, Satoshi; Takenouchi, Osami; Unoki, Gen; Yamakoshi, Yuko; Cunliffe, Vicky; Frearson, Julie; Gordon, Richard; John Harris; Kalloo-Hosein, Heidi; Le, Joelle; Patel, Gita; Simpson, Donald J.; Sherborne, Brad; Thomas, Peter S.; Suzuki, Naotaka; Takimoto-Kamimura, Midori; Kataoka, Ken-Ichiro Journal of Medicinal Chemistry, 2012 , vol. 55, # 15 p. 6700 - 6715

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.19
  • LogP   2.34452
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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