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CS-W001157 4
Total: USD 88.00

Diethyl methylmalonate

  • CAS No. 609-08-5

  • Cat. No. CS-0042420
  • Purity≥97%
  • MDL No.MFCD00009162

*For research and further manufacturing use only, not for direct human use.

Diethyl methylmalonate|CS-0042420

Structure of 609-08-5

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General Information

  • CAS No. 609-08-5
  • Cat. No. CS-0042420
  • Purity ≥97%
  • MDL No. MFCD00009162
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄O₄
  • Molecular Weight 174.19
  • Synonym(s) Propanedioic acid, 2-methyl-, diethyl ester; Diethyl methylmalonate
  • SMILES O=C(OCC)C(C)C(OCC)=O

Description

Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis.Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain.

Synthesis

  • Route1
    • null|null
      105-53-3
    • null|null
      74-88-4
    • ~99%
    • In-stock
      Diethyl methylmalonate|CS-0042420
      609-08-5

    References

    • Arumugam, Subramaniam; McLeod, Dale; Verkade, John G. Journal of Organic Chemistry, 1998 , vol. 63, # 11 p. 3677 - 3679
  • Route2
    • null|null
      105-53-3
    • ~84%
    • In-stock
      Diethyl methylmalonate|CS-0042420
      609-08-5

    References

    • Bayer Aktiengesellschaft Patent: US4567004 A1, 1986 ;
  • Route3
    • null|null
      80073-77-4
    • ~78%
    • In-stock
      Diethyl methylmalonate|CS-0042420
      609-08-5

    References

    • Xu, Qiongfeng; Cheng, Bin; Ye, Xinshan; Zhai, Hongbin Organic Letters, 2009 , vol. 11, # 18 p. 4136 - 4138

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   0.7487
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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