Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,3-Dihydro-1-oxo-1H-indene-4-carbonitrile

  • CAS No. 60899-34-5

  • Cat. No. CS-B0434
  • Purity≥95%
  • MDL No.MFCD01111989

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydro-1-oxo-1H-indene-4-carbonitrile|CS-B0434

Structure of 60899-34-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 60899-34-5
  • Cat. No. CS-B0434
  • Purity ≥95%
  • MDL No. MFCD01111989
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO
  • Molecular Weight None
  • Synonym(s) 4-Cyano-1-indanone
  • SMILES N#CC1=C(CC2)C(C2=O)=CC=C1

Description

This electron-deficient indenone derivative features a conjugated carbonitrile group, enabling direct integration into heterocyclic synthesis. The planar, aromatic core facilitates efficient coupling reactions under mild conditions. Bench-stable and moisture-tolerant, it serves as a robust scaffold for constructing functionalized polycycles in medicinal chemistry and materials science.

Application

2,3-Dihydro-1-oxo-1H-indene-4-carbonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indenone derivatives and heterocyclic scaffolds. Its conjugated enone–nitrile functionality supports diverse transformations including nucleophilic additions, Michael reactions, and transition-metal-catalyzed couplings. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      557-21-1
    • In-stock
      4-Bromo-1-indanone|CS-D0684
      15115-60-3
    • ~58%
    • In-stock
      2,3-Dihydro-1-oxo-1H-indene-4-carbonitrile|CS-B0434
      60899-34-5

    References

    • RECEPTOS, INC.; MARTINBOROUGH, Esther; BOEHM, Marcus, F.; YEAGER, Adam, Richard; TAMIYA, Junko; HUANG, Liming; BRAHMACHARY, Enugurthi; MOORJANI, Manisha Patent: WO2011/60389 A1, 2011 ; Location in patent: Page/Page column 87-88 ; WO 2011/060389 A1
  • Route2

    References

    • US5902803 A1, ; US 5902803 A
  • Route3

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 139, p. 94

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.86
  • LogP   1.68718
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 60899-34-5 sigma60899-34-5 manufacturer60899-34-5 price60899-34-5 structure60899-34-5 SDSbuy 60899-34-560899-34-5 supplier60899-34-5 uses60899-34-5 molecular weightprice of 60899-34-560899-34-5 chemical name formula of 60899-34-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label