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Structure of 605659-03-8
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This 2-(4,4-difluoropiperidin-1-yl)ethanamine features a fluorinated piperidine moiety linked to an ethylamine chain, delivering enhanced metabolic stability and improved membrane permeability. The electron-withdrawing difluoro substitution increases basicity and modulates pharmacokinetic behavior. This scaffold integrates readily into bioactive molecules for medicinal chemistry applications.
2-(4,4-Difluoropiperidin-1-yl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through amide bond formation and reductive amination. Its difluoropiperidine moiety enhances metabolic stability and modulates basicity, while the pendant ethanamine group offers facile functionalization. Bench-stable and compatible with standard purification methods, it facilitates efficient synthesis of targeted compounds in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335-H332-H312
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: