Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(3,4-Dimethylphenyl)hydrazine monohydrochloride

  • CAS No. 60481-51-8

  • Cat. No. CS-W016019
  • Purity≥95%
  • MDL No.MFCD00052270

*For research and further manufacturing use only, not for direct human use.

(3,4-Dimethylphenyl)hydrazine monohydrochloride|CS-W016019

Structure of 60481-51-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 60481-51-8
  • Cat. No. CS-W016019
  • Purity ≥95%
  • MDL No. MFCD00052270
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃ClN₂
  • Molecular Weight 172.66
  • Synonym(s) Eltrombopag impurity 55 (monohydrochloride)
  • SMILES CC1=CC=C(NN)C=C1C.Cl

Description

(3,4-Dimethylphenyl)hydrazine hydrochloride features a substituted hydrazine moiety attached to a methylated phenyl ring, delivering enhanced stability and solubility in polar solvents. This bench-stable reagent integrates readily into C–N bond-forming transformations and serves as a key intermediate in the synthesis of heterocyclic compounds and functionalized aromatic systems under standard conditions.

Application

(3,4-Dimethylphenyl)hydrazine hydrochloride serves as a reliable building block for heterocyclic synthesis, particularly in the construction of pyrazoles and other nitrogen-containing scaffolds. Its stability under standard reaction conditions and ease of purification facilitate efficient access to substituted aromatic hydrazones. The compound exhibits good functional group tolerance and is well-suited for use in medicinal chemistry campaigns requiring regioselective cyclization pathways.

Synthesis

  • Route1
    • null|null
      583-71-1
    • ~52%
    • In-stock
      (3,4-Dimethylphenyl)hydrazine monohydrochloride|CS-W016019
      60481-51-8

    References

    • Kurandina, Daria V.; Eliseenkov, Eugene V.; Ilyin, Petr V.; Boyarskiy, Vadim P. Tetrahedron, 2014 , vol. 70, # 26 p. 4043 - 4048
  • Route2
    • null|null
      95-64-7
    • ~%
    • In-stock
      (3,4-Dimethylphenyl)hydrazine monohydrochloride|CS-W016019
      60481-51-8

    References

    • Angewandte Chemie - International Edition, , vol. 52, # 47 p. 12426 - 12429 Angew. Chem., , vol. 125, # 47 p. 12652 - 12656,4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.01084
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 60481-51-8 sigma60481-51-8 manufacturer60481-51-8 price60481-51-8 structure60481-51-8 SDSbuy 60481-51-860481-51-8 supplier60481-51-8 uses60481-51-8 molecular weightprice of 60481-51-860481-51-8 chemical name formula of 60481-51-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label