tert-Butyl 2-cyclohexylhydrazine-1-carboxylate

Name: tert-Butyl 2-cyclohexylhydrazine-1-carboxylate
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CAS No. 60295-21-8
Cat. No. CS-0046930
Purity≥97%
MDL No.None

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tert-Butyl 2-cyclohexylhydrazine-1-carboxylate|CS-0046930

Structure of 60295-21-8

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General Information

CAS No. 60295-21-8
Cat. No. CS-0046930
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₂₂N₂O₂
Molecular Weight 214.30
Synonym(s) Tert-Butyl 2-Cyclohexylhydrazinecarboxylate(WX684424)
SMILES CC(C)(C)OC(NNC1CCCCC1)=O

Description

tert-Butyl 2-cyclohexylhydrazine-1-carboxylate features a sterically hindered hydrazine moiety anchored to a cyclohexyl group, enabling selective reactivity in nitrogen-directed transformations. The tert-butyl carbamate handle offers stability under standard conditions and facilitates straightforward deprotection during synthetic sequences. This compound serves as a key intermediate in the construction of complex heterocycles and bioactive scaffolds.

Application

tert-Butyl 2-cyclohexylhydrazine-1-carboxylate serves as a stable, bench-friendly hydrazine building block for the synthesis of heterocyclic scaffolds and bioactive molecules. Its cyclohexylhydrazine moiety enables efficient coupling reactions and facilitates access to diverse nitrogen-containing frameworks via cyclization or functional group interconversions. The tert-butyl carbamate protects the hydrazine under standard reaction conditions, allowing selective deprotection and broad functional group tolerance in multistep syntheses.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

TPSA 50.36
LogP 2.3484
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Hydrazine

Building Blocks Skeleton Fatty ring compounds Cyclohexane compounds

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tert-Butyl 2-cyclohexylhydrazine-1-carboxylate

CAS No. 60295-21-8

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