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CS-W001157 4
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1-(4-Amino-2-methoxyphenyl)ethanone

  • CAS No. 60207-18-3

  • Cat. No. CS-0043830
  • Purity≥98%
  • MDL No.MFCD11848247

*For research and further manufacturing use only, not for direct human use.

1-(4-Amino-2-methoxyphenyl)ethanone|CS-0043830

Structure of 60207-18-3

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General Information

  • CAS No. 60207-18-3
  • Cat. No. CS-0043830
  • Purity ≥98%
  • MDL No. MFCD11848247
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) 1-(4-Amino-2-methoxy-phenyl)-ethanone
  • SMILES COC1=C(C=CC(N)=C1)C(C)=O

Description

1-(4-Amino-2-methoxyphenyl)ethanone features a phenolic amine moiety flanked by methoxy and ketone functionalities, enabling direct integration into diverse synthetic scaffolds. This bench-stable compound serves as a key intermediate in the construction of bioactive heterocycles and functionalized aryl ketones under standard conditions.

Application

1-(4-Amino-2-methoxyphenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted aniline derivatives and heterocyclic scaffolds. Its amino and methoxy groups offer orthogonal reactivity for downstream functionalization, while the ketone moiety facilitates nucleophilic addition and enolization reactions. Bench-stable and readily purified by crystallization, it functions effectively in standard coupling and cyclization protocols common to API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.48
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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