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CS-W001157 4
Total: USD 88.00

TPO-L

  • CAS No. 84434-11-7

  • Cat. No. CS-W018680
  • Purity≥97%
  • MDL No.MFCD08692488

*For research and further manufacturing use only, not for direct human use.

TPO-L|CS-W018680

Structure of 84434-11-7

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General Information

  • CAS No. 84434-11-7
  • Cat. No. CS-W018680
  • Purity ≥97%
  • MDL No. MFCD08692488
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₁O₃P
  • Molecular Weight 316.33
  • Synonym(s) None
  • SMILES O=C(P(OCC)(C1=CC=CC=C1)=O)C2=C(C)C=C(C)C=C2C

Description

TPO-L is a bench-stable, moisture-tolerant phosphine ligand featuring a sterically hindered, electron-rich architecture. This design enhances catalyst longevity and reactivity in palladium-catalyzed cross-coupling reactions. The ligand integrates seamlessly into complex synthetic sequences, delivering high yields under standard conditions.

Application

TPO-L serves as a robust, bench-stable building block for the synthesis of complex heterocycles and bioactive scaffolds. Its well-defined reactivity enables efficient coupling in standard cross-coupling protocols, offering high functional group tolerance and straightforward purification. Widely employed in medicinal chemistry and process R&D, TPO-L facilitates rapid access to structurally diverse libraries with predictable transformation outcomes.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H411
Precautionary Statements : P261-P272-P273-P280-P302+P352-P362+P364-P391-P501

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   4.39216
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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