Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Chloro-2-methyl-6-(trifluoromethyl)pyrimidine

  • CAS No. 5993-98-6

  • Cat. No. CS-W006266
  • Purity≥97%
  • MDL No.MFCD03265399

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-methyl-6-(trifluoromethyl)pyrimidine|CS-W006266

Structure of 5993-98-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5993-98-6
  • Cat. No. CS-W006266
  • Purity ≥97%
  • MDL No. MFCD03265399
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClF₃N₂
  • Molecular Weight 196.56
  • Synonym(s) 4-CHLORO-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE
  • SMILES ClC1=NC(=NC(=C1)C(F)(F)F)C

Description

4-Chloro-2-methyl-6-(trifluoromethyl)pyrimidine is a trifluoromethyl-substituted pyrimidine featuring a chlorine at C4 and a methyl group at C2, delivering enhanced electron-withdrawing character. This scaffold enables efficient coupling in cross-coupling reactions and serves as a key building block for pharmaceutical intermediates. The trifluoromethyl moiety imparts metabolic stability and improved membrane permeability.

Application

4-Chloro-2-methyl-6-(trifluoromethyl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the chloropyrimidine core offers predictable reactivity with nucleophiles, facilitating rapid diversification. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it well-suited for high-throughput synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.45722
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5993-98-6 sigma5993-98-6 manufacturer5993-98-6 price5993-98-6 structure5993-98-6 SDSbuy 5993-98-65993-98-6 supplier5993-98-6 uses5993-98-6 molecular weightprice of 5993-98-65993-98-6 chemical name formula of 5993-98-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label