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CS-W001157 4
Total: USD 88.00

Anticonvulsant agent 3

  • CAS No. 59565-51-4

  • Cat. No. CS-0034424
  • Purity≥98%
  • MDL No.MFCD00981035

*For research and further manufacturing use only, not for direct human use.

Anticonvulsant agent 3|CS-0034424

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General Information

  • CAS No. 59565-51-4
  • Cat. No. CS-0034424
  • Purity ≥98%
  • MDL No. MFCD00981035
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆FN₃S
  • Molecular Weight 195.22
  • Synonym(s) None
  • SMILES NC1=NN=C(C2=C(F)C=CC=C2)S1

Description

Anticonvulsant agent 3 delivers robust seizure suppression through targeted modulation of voltage-gated sodium channels. This bench-stable compound features a trifluoromethyl-substituted heterocyclic core, enhancing membrane permeability and metabolic resilience. It integrates seamlessly into neuropharmacological screening workflows, offering consistent efficacy in preclinical models without significant off-target engagement.

Application

Anticonvulsant agent 3 serves as a versatile building block for CNS-targeted pharmaceuticals, enabling efficient construction of heterocyclic scaffolds via established coupling and cyclization protocols. Its functional group tolerance supports robust late-stage modifications, while bench-stable properties facilitate reliable handling in multi-step syntheses.

Synthesis

  • Route1
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      2107-16-6
    • ~%
    • In-stock
      Anticonvulsant agent 3|CS-0034424
      59565-51-4

    References

    • Turner, Stephen; Myers, Malcolm; Gadie, Brian; Nelson, Anthony J.; Pape, Robin; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 902 - 906
  • Route2

    References

    • Foroumadi; Tabatabai; Gitinezhad; Zarrindast; Shafiee Pharmacy and Pharmacology Communications, 2000 , vol. 6, # 1 p. 31 - 33
  • Route3

    References

    • Foroumadi; Tabatabai; Gitinezhad; Zarrindast; Shafiee Pharmacy and Pharmacology Communications, 2000 , vol. 6, # 1 p. 31 - 33

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.9264
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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