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CS-W001157 4
Total: USD 88.00

2-Fluorobenzaldehyde

  • CAS No. 446-52-6

  • Cat. No. CS-W008891
  • Purity≥95%
  • MDL No.MFCD00003302

*For research and further manufacturing use only, not for direct human use.

2-Fluorobenzaldehyde|CS-W008891

Structure of 446-52-6

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General Information

  • CAS No. 446-52-6
  • Cat. No. CS-W008891
  • Purity ≥95%
  • MDL No. MFCD00003302
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅FO
  • Molecular Weight 124.11
  • Synonym(s) 2-Fluorobenzaldeyde; 2-Fluorobenzaldehyde
  • SMILES FC1=CC=CC=C1C=O

Description

2-Fluorobenzaldehyde serves as a key building block in synthetic organic chemistry, featuring a fluorinated aromatic ring that enhances electronic and metabolic stability. The aldehyde group enables direct functionalization in coupling reactions, while the ortho-fluoro substitution influences regioselectivity and reactivity. This compound integrates readily into pharmaceutical intermediates and agrochemical scaffolds under standard conditions.

Synthesis

  • Route1
    • null|null
      1159505-77-7
    • ~84%
    • In-stock
      2-Fluorobenzaldehyde|CS-W008891
      446-52-6

    References

    • The Scripps Research Insitiute Patent: US2012/59179 A1, 2012 ; Location in patent: Page/Page column 18 ;
  • Route2

    References

    • Saffar-Teluri, Ali Research on Chemical Intermediates, 2013 , vol. 39, # 7 p. 3337 - 3343
  • Route3
    • null|null
      394-47-8
    • ~82%
    • In-stock
      2-Fluorobenzaldehyde|CS-W008891
      446-52-6

    References

    • Bayer Chemicals AG Patent: EP1389608 A1, 2004 ; Location in patent: Page/Page column 6 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1989
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H315
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.6382
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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