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CS-W001157 4
Total: USD 88.00

Boc-Glu(Obzl)-OMe

  • CAS No. 59279-58-2

  • Cat. No. CS-0154519
  • Purity≥97%
  • MDL No.MFCD00190792

*For research and further manufacturing use only, not for direct human use.

Boc-Glu(Obzl)-OMe|CS-0154519

Structure of 59279-58-2

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General Information

  • CAS No. 59279-58-2
  • Cat. No. CS-0154519
  • Purity ≥97%
  • MDL No. MFCD00190792
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₅NO₆
  • Molecular Weight 351.39
  • Synonym(s) N-ALPHA-T-BUTOXYCARBONYL-L-GLUTAMIC ACID GAMMA-BENZYL ESTER ALPHA-METHYL ESTER
  • SMILES CC(C)(OC(N[C@H](C(OC)=O)CCC(OCC1=CC=CC=C1)=O)=O)C

Description

Boc-Glu(Obzl)-OMe serves as a protected glutamic acid derivative featuring a tert-butoxycarbonyl group at the α-amino terminus and a benzyl ester at the side-chain carboxylate. This configuration enables stable incorporation into peptide synthesis sequences, where the side-chain protection prevents unwanted reactivity while maintaining compatibility with standard deprotection protocols.

Application

Boc-Glu(Obzl)-OMe serves as a versatile dipeptide building block for the synthesis of peptide-based pharmaceuticals and bioactive molecules. The Boc group provides stable protection of the N-terminus, while the benzyl ester (Obzl) and methyl ester (OMe) functionalities enable selective deprotection and efficient coupling reactions. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for solid-phase and solution-phase peptide synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.93
  • LogP   2.5763
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   7

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