(+)-Nipecotic acid

Name: (+)-Nipecotic acid
Brand: ChemScene
Availability: InStock
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CAS No. 59045-82-8
Cat. No. CS-W013451
Purity≥98%
MDL No.MFCD01630807

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 59045-82-8
Cat. No. CS-W013451
Purity ≥98%
MDL No. MFCD01630807
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₁NO₂
Molecular Weight 129.16
Synonym(s) (+)-β-Homoproline; (+)-Hexahydronicotinic acid; (+)-3-Carboxypiperidine
SMILES O=C([C@]1([H])CNCCC1)O

Description

(+)-Nipecotic acid is a stereodefined, bench-stable γ-aminobutyric acid (GABA) analog featuring a rigid cyclic structure that enhances its metabolic stability. This derivative serves as a potent and selective inhibitor of GABA transporters, enabling precise modulation of synaptic GABA levels in neuropharmacological studies. Its defined stereochemistry ensures consistent biological activity across experimental systems.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 49.33
LogP 0.0706
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Biochemistry Biochemicals and Reagents Pharmaceutical Research Reagents Neurotransmitter Agent Ingredients

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids non-Proteinogenic Amino Acids

Biochemistry Pharmaceutical Development and Drug Discovery Research Pharmaceutical Research Reagents Neurotransmitter Agent Ingredients

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(+)-Nipecotic acid

CAS No. 59045-82-8

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