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CS-W001157 4
Total: USD 88.00

(S)-Boc-nipecotic acid

  • CAS No. 88495-54-9

  • Cat. No. CS-W002899
  • Purity≥96%
  • MDL No.MFCD02179172

*For research and further manufacturing use only, not for direct human use.

(S)-Boc-nipecotic acid|CS-W002899

Structure of 88495-54-9

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General Information

  • CAS No. 88495-54-9
  • Cat. No. CS-W002899
  • Purity ≥96%
  • MDL No. MFCD02179172
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.28
  • Synonym(s) None
  • SMILES OC(=O)[C@H]1CCCN(C1)C(=O)OC(C)(C)C

Description

(S)-Boc-nipecotic acid is a stereochemically defined, bench-stable building block for asymmetric synthesis. The Boc-protected pyrrolidine moiety enables direct incorporation into peptide-like scaffolds and complex alkaloid architectures. This derivative features enhanced solubility in organic media and tolerance to standard coupling conditions, streamlining access to biologically relevant heterocyclic compounds.

Application

(S)-Boc-nipecotic acid serves as a stereochemically defined building block for the synthesis of saturated nitrogen heterocycles and bioactive alkaloid scaffolds. Its stability, ease of purification, and compatibility with standard peptide coupling protocols enable efficient incorporation into complex molecular architectures. The Boc group provides orthogonal protection for amine functionalities during multi-step syntheses, facilitating selective transformations in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H410
Precautionary Statements : P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.7181
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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