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(s)-2-Amino-5-methoxytetralin hydrochloride

  • CAS No. 58349-17-0

  • Cat. No. CS-M1827
  • Purity≥95%
  • MDL No.MFCD08443937

*For research and further manufacturing use only, not for direct human use.

(s)-2-Amino-5-methoxytetralin hydrochloride|CS-M1827

Structure of 58349-17-0

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General Information

  • CAS No. 58349-17-0
  • Cat. No. CS-M1827
  • Purity ≥95%
  • MDL No. MFCD08443937
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO
  • Molecular Weight 213.70
  • Synonym(s) None
  • SMILES N[C@@H]1CC2=C(C(OC)=CC=C2)CC1.Cl

Description

This chiral tetrahydronaphthalene amine features a bench-stable hydrochloride salt form, enabling straightforward handling and solubility in aqueous media. The methoxy group enhances electron density at the aromatic ring, while the stereogenic center ensures precise stereochemical control in asymmetric synthesis.

Application

(S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride serves as a chiral building block for bioactive heterocycles and medicinal chemistry libraries. Its tetrahydroisoquinoline core enables efficient functionalization via electrophilic substitution, reductive amination, and transition-metal-catalyzed coupling. The hydrochloride salt ensures excellent bench stability, solubility, and ease of purification, facilitating scalable synthesis and downstream derivatization in API development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.933
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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