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CS-W001157 4
Total: USD 88.00

4-Bromo-2-methylaniline

  • CAS No. 583-75-5

  • Cat. No. CS-D1131
  • Purity≥97%
  • MDL No.MFCD00007825

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-methylaniline|CS-D1131

Structure of 583-75-5

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General Information

  • CAS No. 583-75-5
  • Cat. No. CS-D1131
  • Purity ≥97%
  • MDL No. MFCD00007825
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrN
  • Molecular Weight 186.05
  • Synonym(s) 5-Bromo-2-aminotoluene
  • SMILES NC1=CC=C(Br)C=C1C

Description

4-Bromo-2-methylaniline was used in the preparation of 4-Bromo-2-methylphenol.

Application

4-Bromo-2-methylaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of both bromo and methylamino functionalities. Its ortho-methyl group enhances regioselectivity in subsequent coupling reactions, while the aniline handle facilitates palladium-catalyzed cross-couplings, electrophilic substitutions, and amide formation. Bench-stable and readily purified by distillation or recrystallization, it functions efficiently in multi-step syntheses requiring functional group compatibility and predictable reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.33972
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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