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CS-W001157 4
Total: USD 88.00

(S)-2-Fluoropropanoic acid

  • CAS No. 57965-29-4

  • Cat. No. CS-0436042
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Fluoropropanoic acid|CS-0436042

Structure of 57965-29-4

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General Information

  • CAS No. 57965-29-4
  • Cat. No. CS-0436042
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅FO₂
  • Molecular Weight 92.07
  • Synonym(s) (S)-2-Fluoropropionic acid
  • SMILES OC([C@@H](F)C)=O

Description

(S)-2-Fluoropropanoic acid is a chiral fluorinated aliphatic carboxylic acid featuring a stereogenic center at the C2 position. This configuration imparts distinct reactivity and recognition properties in asymmetric synthesis, particularly in the construction of fluorinated building blocks for medicinal chemistry. The molecule exhibits enhanced metabolic stability compared to its non-fluorinated analogs, making it valuable for bioactive compound design. Its bench-stable nature facilitates handling under standard laboratory conditions.

Application

(S)-2-Fluoropropanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated bioactive molecules through established enantioselective transformations. Its stability under standard reaction conditions and compatibility with common functional groups facilitate efficient incorporation into complex scaffolds. The molecule functions as a key intermediate in the construction of fluorinated analogs for drug discovery, particularly in optimizing metabolic stability and membrane permeability.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H314-H319
Precautionary Statements : P210-P264-P270-P280-P304+P340-P330-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.429
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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