(R)-2-Fluoropropanoic acid

Name: (R)-2-Fluoropropanoic acid
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CAS No. 75244-22-3
Cat. No. CS-0435455
Purity≥96%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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General Information

CAS No. 75244-22-3
Cat. No. CS-0435455
Purity ≥96%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₅FO₂
Molecular Weight 92.07
Synonym(s) (2R)-2-Fluoropropanoic acid
SMILES C[C@@H](F)C(O)=O

Description

(R)-2-Fluoropropanoic acid is a chiral fluorinated carboxylic acid featuring a stereodefined configuration at the alpha carbon. This bench-stable, moisture-tolerant reagent integrates readily into asymmetric synthesis workflows, where its electron-withdrawing fluorine imparts enhanced reactivity and selectivity in enantioselective transformations.

Application

(R)-2-Fluoropropanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated bioactive molecules through established functional group transformations. Its bench-stable nature and defined stereochemistry facilitate reliable incorporation into complex scaffolds, particularly in the development of protease inhibitors and other targeted therapeutics.

Safety Information

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Signal Word : N/A	UN#: N/A
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Precautionary Statements : N/A

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Computational Chemistry Data

TPSA 37.3
LogP 0.429
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Fluoropropanoic acid

CAS No. 75244-22-3

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