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CS-W001157 4
Total: USD 88.00

1-(2-Methoxyphenyl)ethanone

  • CAS No. 579-74-8

  • Cat. No. CS-W016325
  • Purity≥97%
  • MDL No.MFCD00008725

*For research and further manufacturing use only, not for direct human use.

1-(2-Methoxyphenyl)ethanone|CS-W016325

Structure of 579-74-8

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General Information

  • CAS No. 579-74-8
  • Cat. No. CS-W016325
  • Purity ≥97%
  • MDL No. MFCD00008725
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₂
  • Molecular Weight 150.18
  • Synonym(s) 2'-Methoxyacetophenone
  • SMILES COC1=C(C=CC=C1)C(C)=O

Description

1-(2-Methoxyphenyl)ethanone features a benzene ring bearing both methoxy and acetyl substituents in ortho configuration, delivering enhanced solubility and stability under standard bench conditions. This electron-rich aryl ketone integrates readily into synthetic sequences involving nucleophilic addition or coupling reactions, offering predictable reactivity for medicinal chemistry and materials synthesis applications.

Application

1-(2-Methoxyphenyl)ethanone serves as a versatile aryl ketone building block in medicinal chemistry and natural product synthesis. Its ortho-methoxy substitution enhances electrophilic reactivity while maintaining bench stability. The molecule facilitates efficient Friedel-Crafts acylations, nucleophilic additions, and transition-metal-catalyzed couplings, enabling rapid access to substituted benzene derivatives and heterocyclic scaffolds under standard reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.8978
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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