Lot numbers can be found on the outside label of a product:
Methyl 2-(4-bromophenyl)-2-oxoacetate
-
CAS No. 57699-28-2
- Cat. No. CS-W022782
- Purity≥98%
- MDL No.MFCD00193630
*For research and further manufacturing use only, not for direct human use.
Structure of 57699-28-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 57699-28-2
- Cat. No. CS-W022782
- Purity ≥98%
- MDL No. MFCD00193630
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₇BrO₃
- Molecular Weight 243.05
- Synonym(s) methyl (p-bromophenyl)glyoxylate
- SMILES O=C(OC)C(C1=CC=C(Br)C=C1)=O
Description
Methyl 2-(4-bromophenyl)-2-oxoacetate features a brominated aromatic ring coupled to a β-keto ester moiety, enabling direct functionalization in cross-coupling and heterocycle synthesis. The electron-deficient aryl group enhances reactivity in palladium-catalyzed transformations, while the ester functionality supports further derivatization under mild conditions. This compound serves as a key building block for pharmaceutical intermediates and advanced materials.
Application
Methyl 2-(4-bromophenyl)-2-oxoacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted benzophenones and heterocyclic scaffolds. Its brominated aryl group facilitates palladium-catalyzed cross-coupling reactions, while the α-keto ester functionality supports nucleophilic additions and condensation processes. The compound exhibits good bench stability and ease of purification, making it well-suited for iterative synthesis and scale-up applications in medicinal chemistry and process development.
Synthesis
-
Route1
-
264881-99-4 - ~70%
-
In-stock
57699-28-2
References
-
Guo, Zhenqiu; Huang, Haoxi; Fu, Qingquan; Hu, Wenhao Synlett, 2006 , # 15 p. 2486 - 2488
-
-
Route2
-
67-56-1
-
In-stock
99-90-1 - ~75%
-
In-stock
57699-28-2
References
-
Zhuang, Jing; Wang, Changqing; Xie, Fang; Zhang, Wanbin Tetrahedron, 2009 , vol. 65, # 47 p. 9797 - 9800
-
-
Route3
-
186581-53-3
- ~%
-
In-stock
57699-28-2
References
-
Sheppeck, James; Dhar, T.G. Murali; Doweyko, Lidia; Gilmore, John; Weinstein, David; Xiao, Hai-Yun; Yang, Bingwei V.; Doweyko, Arthur M. Patent: US2006/154973 A1, 2006 ; Location in patent: Page/Page column 47 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.37
- LogP 1.8048
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 2-(4-bromophenyl)-2-oxoacetate sigmaMethyl 2-(4-bromophenyl)-2-oxoacetate manufacturerMethyl 2-(4-bromophenyl)-2-oxoacetate priceMethyl 2-(4-bromophenyl)-2-oxoacetate structureMethyl 2-(4-bromophenyl)-2-oxoacetate SDSbuy Methyl 2-(4-bromophenyl)-2-oxoacetateMethyl 2-(4-bromophenyl)-2-oxoacetate supplierMethyl 2-(4-bromophenyl)-2-oxoacetate usesMethyl 2-(4-bromophenyl)-2-oxoacetate molecular weightprice of Methyl 2-(4-bromophenyl)-2-oxoacetateMethyl 2-(4-bromophenyl)-2-oxoacetate chemical name formula of Methyl 2-(4-bromophenyl)-2-oxoacetate