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CS-W001157 4
Total: USD 88.00

2-Methoxyphenothiazine

  • CAS No. 1771-18-2

  • Cat. No. CS-W012974
  • Purity≥95%
  • MDL No.MFCD00037838

*For research and further manufacturing use only, not for direct human use.

2-Methoxyphenothiazine|CS-W012974

Structure of 1771-18-2

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General Information

  • CAS No. 1771-18-2
  • Cat. No. CS-W012974
  • Purity ≥95%
  • MDL No. MFCD00037838
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁NOS
  • Molecular Weight 229.30
  • Synonym(s) 2-Methoxy-10H-phenothiazine
  • SMILES COC1=CC(NC2=CC=CC=C2S3)=C3C=C1

Description

2-Methoxyphenothiazine delivers a robust, electron-rich heterocyclic scaffold with enhanced solubility and stability under standard conditions. This bench-stable compound features a methoxy group at the 2-position, which modulates electronic properties while improving handling characteristics. It serves as a key building block in the synthesis of advanced materials and functional dyes.

Application

2-Methoxyphenothiazine serves as a stable, bench-ready heterocyclic building block for medicinal chemistry and materials science applications. Its methoxy-substituted phenothiazine core exhibits robust functional group tolerance and facilitates direct C–H arylation or palladium-catalyzed coupling reactions. The compound functions effectively in the synthesis of redox-active dyes, organic semiconductors, and bioactive scaffolds requiring extended π-conjugation and electron-donating character.

Synthesis

  • Route1
    • In-stock
      3-Methoxy-N-phenylaniline|CS-W010505
      101-16-6
    • ~90%
    • null|null
      61174-11-6
    • In-stock
      2-Methoxyphenothiazine|CS-W012974
      1771-18-2

    References

    • Journal of Heterocyclic Chemistry, , vol. 49, # 2 p. 438 - 441
  • Route2
    • null|null
      4726-28-7
    • ~%
    • In-stock
      2-Methoxyphenothiazine|CS-W012974
      1771-18-2

    References

    • Angewandte Chemie - International Edition, , vol. 49, # 7 p. 1291 - 1294
  • Route3
    • null|null
      74497-02-2
    • ~%
    • null|null
      61174-11-6
    • In-stock
      2-Methoxyphenothiazine|CS-W012974
      1771-18-2

    References

    • Journal of Heterocyclic Chemistry, , vol. 49, # 2 p. 438 - 441

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H319-H335-H372-H411
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   3.9034
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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