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CS-W001157 4
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3-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-amine

  • CAS No. 57648-83-6

  • Cat. No. CS-0244798
  • Molecule weight221.30
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-amine|CS-0244798

Structure of 57648-83-6

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General Information

  • CAS No. 57648-83-6
  • Cat. No. CS-0244798
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉N₅
  • Molecular Weight 221.30
  • Synonym(s) 3-(4-Pyrimidin-2-ylpiperazin-1-yl)propan-1-amine
  • SMILES NCCCN1CCN(C2=NC=CC=N2)CC1

Synthesis

  • Route1
    • null|null
      206053-35-2
    • ~84%
    • 3-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-amine|CS-0244798
      57648-83-6

    References

    • Gagliardi, Stefania; Nadler, Guy; Consolandi, Emanuela; Parini, Carlo; Morvan, Marcel; Legave, Marie-Noeelle; Belfiore, Pietro; Zocchetti, Andrea; Clarke, Geoffrey D.; James, Ian; Nambi, Ponnal; Gowen, Maxine; Farina, Carlo Journal of Medicinal Chemistry, 1998 , vol. 41, # 10 p. 1568 - 1573
  • Route2
    • null|null
      138274-09-6
    • ~76%
    • 3-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-amine|CS-0244798
      57648-83-6

    References

    • Ishizumi; Kojima; Antoku Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300
  • Route3

    References

    • He, Xiao Shu; Woodruff, Kristine; Brodbeck, Robbin Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 18 p. 2399 - 2402

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H318-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.28
  • LogP   -0.0526
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   4

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