2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

Name: 2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 942922-07-8
Cat. No. CS-0091577
Purity≥97%
MDL No.MFCD08669592

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine|CS-0091577

Structure of 942922-07-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 942922-07-8
Cat. No. CS-0091577
Purity ≥97%
MDL No. MFCD08669592
Storage -20°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₅BN₄O₂
Molecular Weight 304.20
Synonym(s) 2-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
SMILES CC1(C)C(C)(C)OB(C2=CN=C(N3CCN(C)CC3)N=C2)O1

Description

This pyrimidine derivative features a 4-methylpiperazine moiety paired with a boronate ester group, enabling efficient Suzuki-Miyaura cross-coupling under standard conditions. The tetramethyl-substituted dioxaborolane enhances stability and reactivity, while the electron-rich piperazine facilitates functionalization in late-stage diversification. Designed for streamlined synthesis in medicinal chemistry and materials science.

Application

2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pyrimidine core provides a rigid, electron-deficient scaffold compatible with diverse nucleophiles, while the pinacol boronate ester ensures excellent stability and ease of handling. This compound facilitates efficient C–C bond formation under mild conditions, enabling rapid access to functionalized heterocyclic architectures relevant in medicinal chemistry and materials science.

Synthesis

Route1
- 141302-36-5
- In-stock
  
  73183-34-3
- ~%
- In-stock
  
  942922-07-8
References
- WO2009/74812 A1, ; Page/Page column 68 ; WO 2009/074812 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 50.72
LogP 0.5276
H_Acceptors 6
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

942922-07-8 sigma942922-07-8 manufacturer942922-07-8 price942922-07-8 structure942922-07-8 SDSbuy 942922-07-8942922-07-8 supplier942922-07-8 uses942922-07-8 molecular weightprice of 942922-07-8942922-07-8 chemical name formula of 942922-07-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

CAS No. 942922-07-8

Recommended Products