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CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate

  • CAS No. 479691-42-4

  • Cat. No. CS-W023000
  • Purity≥97%
  • MDL No.MFCD09743711

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate|CS-W023000

Structure of 479691-42-4

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General Information

  • CAS No. 479691-42-4
  • Cat. No. CS-W023000
  • Purity ≥97%
  • MDL No. MFCD09743711
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉ClN₄O₂
  • Molecular Weight 298.77
  • Synonym(s) None
  • SMILES O=C(N1CCN(C2=NC=CC(Cl)=N2)CC1)OC(C)(C)C

Synthesis

  • Route1
    • In-stock
      4,6-Dichloropyrimidine|CS-W018513
      1193-21-1
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~94%
    • In-stock
      tert-Butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate|CS-W023000
      479691-42-4

    References

    • WO2009/145360 A1, ; Page/Page column 116 ; WO 2009/145360 A1
  • Route2
    • null|null
      3934-20-1
    • In-stock
      tert-Butyl 4-methylpiperazine-1-carboxylate|CS-0042580
      53788-49-1
    • ~73%
    • In-stock
      tert-Butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate|CS-W023000
      479691-42-4

    References

    • Bioorganic and Medicinal Chemistry, , vol. 22, # 4 p. 1468 - 1478
  • Route3
    • null|null
      3934-20-1
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~%
    • In-stock
      tert-Butyl 4-(2-chloropyrimidin-4-yl)piperazine-1-carboxylate|CS-W003039
      221050-88-0
    • In-stock
      tert-Butyl 4-(4-chloropyrimidin-2-yl)piperazine-1-carboxylate|CS-W023000
      479691-42-4

    References

    • US2005/176722 A1, ; Page/Page column 20; 22 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.1871
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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