7-Bromo-4-chloroquinazoline

Name: 7-Bromo-4-chloroquinazoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 573675-55-5
Cat. No. CS-D0031
Purity≥95%
MDL No.MFCD06657216

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 573675-55-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 573675-55-5
Cat. No. CS-D0031
Purity ≥95%
MDL No. MFCD06657216
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₄BrClN₂
Molecular Weight 243.49
Synonym(s) 7-Bromo-4-chloro-quizoline
SMILES ClC1=C2C=CC(Br)=CC2=NC=N1

Description

7-Bromo-4-chloroquinazoline is a halogenated quinazoline scaffold featuring bromine at the 7-position and chlorine at the 4-position, enabling selective functionalization in medicinal chemistry. This electron-deficient heterocycle integrates readily into kinase inhibitor architectures and serves as a key intermediate for bioactive molecule synthesis under standard conditions.

Application

7-Bromo-4-chloroquinazoline serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity facilitates selective C–C and C–heteroatom bond formation, while the quinazoline core provides a rigid scaffold for kinase inhibitor development. Bench-stable and readily purified, it functions effectively in standard synthetic workflows.

Synthesis

Route1
- In-stock
  
  194851-16-6
- ~83%
- In-stock
  
  573675-55-5
References
- MERCK PATENT GMBH; Mederski, Werner; Fuchss, Thomas; Zenke, Frank Patent: US2013/12489 A1, 2013 ; Location in patent: Paragraph 0183 ;
Route2
- In-stock
  
  20776-50-5
- ~%
- In-stock
  
  573675-55-5
References
- US2013/12489 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 25.78
LogP 3.0457
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

7-Bromo-4-chloroquinazoline sigma7-Bromo-4-chloroquinazoline manufacturer7-Bromo-4-chloroquinazoline price7-Bromo-4-chloroquinazoline structure7-Bromo-4-chloroquinazoline SDSbuy 7-Bromo-4-chloroquinazoline7-Bromo-4-chloroquinazoline supplier7-Bromo-4-chloroquinazoline uses7-Bromo-4-chloroquinazoline molecular weightprice of 7-Bromo-4-chloroquinazoline7-Bromo-4-chloroquinazoline chemical name formula of 7-Bromo-4-chloroquinazoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

7-Bromo-4-chloroquinazoline

CAS No. 573675-55-5

Recommended Products