8-Bromo-4-chloroquinazoline

Name: 8-Bromo-4-chloroquinazoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 125096-72-2
Cat. No. CS-D0030
Purity≥97%
MDL No.MFCD09738589

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 125096-72-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

8-Bromo-4-chloroquinazoline is a heterocyclic compound featuring bromine and chlorine substituents at the 8- and 4-positions of the quinazoline core. This electron-deficient scaffold enables direct incorporation into bioactive molecules, particularly kinase inhibitors and fluorescent probes. The dual halogenation enhances reactivity in palladium-catalyzed cross-coupling reactions, facilitating rapid diversification. Bench-stable and moisture-tolerant, it serves as a robust building block for medicinal chemistry campaigns requiring precise substitution patterns.

Application

8-Bromo-4-chloroquinazoline serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct functionalization at both the 4- and 8-positions via palladium-catalyzed cross-coupling. Its orthogonal halogen reactivity profile facilitates sequential derivatization, while its bench-stable solid form simplifies handling and purification in medicinal chemistry campaigns.

General Information

CAS No. 125096-72-2
Cat. No. CS-D0030
Purity ≥97%
MDL No. MFCD09738589
Storage -20°C, stored under nitrogen, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₄BrClN₂
Molecular Weight 243.49
Synonym(s) None
SMILES ClC1=C2C=CC=C(Br)C2=NC=N1

Computational Chemistry Data

TPSA 25.78
LogP 3.0457
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Quinazoline compounds

Key Words

8-Bromo-4-chloroquinazoline sigma8-Bromo-4-chloroquinazoline manufacturer8-Bromo-4-chloroquinazoline price8-Bromo-4-chloroquinazoline structure8-Bromo-4-chloroquinazoline SDSbuy 8-Bromo-4-chloroquinazoline8-Bromo-4-chloroquinazoline supplier8-Bromo-4-chloroquinazoline uses8-Bromo-4-chloroquinazoline molecular weightprice of 8-Bromo-4-chloroquinazoline8-Bromo-4-chloroquinazoline chemical name formula of 8-Bromo-4-chloroquinazoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

8-Bromo-4-chloroquinazoline

CAS No. 125096-72-2

Recommended Products