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CS-W001157 4
Total: USD 88.00

2,2-Dihydroxyacetic acid

  • CAS No. 563-96-2

  • Cat. No. CS-0031458
  • Purity≥95%
  • MDL No.MFCD00127974

*For research and further manufacturing use only, not for direct human use.

2,2-Dihydroxyacetic acid|CS-0031458

Structure of 563-96-2

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General Information

  • CAS No. 563-96-2
  • Cat. No. CS-0031458
  • Purity ≥95%
  • MDL No. MFCD00127974
  • Storage RT, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₄O₄
  • Molecular Weight 92.05
  • Synonym(s) None
  • SMILES O=C(C(O)O)O

Description

DBCO-PEG9-DBCO is a click chemistry linker with two DBCO groups and a hydrophilic PEG spacer arm. DBCO is reactive with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. The hydrophilic PEG9 arm increase water solubility and membrane permability.

Application

2,2-Dihydroxyacetic acid serves as a stable, bench-ready synthon for the construction of α-hydroxy acid derivatives and glycolic acid-based scaffolds. Its dual hydroxyl functionality enables straightforward derivatization in standard protecting group strategies and facilitates use in multistep synthesis of biologically relevant motifs. The compound exhibits good solubility and stability under ambient conditions, simplifying handling and purification in routine organic workflows.

Synthesis

  • Route1
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4
    • ~%
    • In-stock
      2,2-Dihydroxyacetic acid|CS-0031458
      563-96-2

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 24, p. 2532,2539, 2541 Acta Chemica Scandinavica, Series A: Physical and Inorganic Chemistry, , vol. 28, p. 162,167
  • Route2
    • null|null
      7664-93-9
    • null|null
      7732-18-5
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4
    • ~%
    • In-stock
      2,2-Dihydroxyacetic acid|CS-0031458
      563-96-2

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 24, p. 2532,2539, 2541 Acta Chemica Scandinavica, Series A: Physical and Inorganic Chemistry, , vol. 28, p. 162,167

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H290-H315-H317-H318
Precautionary Statements : P234-P261-P264-P272-P280-P302+P352-P362+P364-P390-P406-P501

Quality Control

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Computational Chemistry Data

  • TPSA   85.87
  • LogP   -1.5548
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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