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Ethyl 2-thioxo-2,3-dihydrothiazole-4-carboxylate

  • CAS No. 56232-75-8

  • Cat. No. CS-0095184
  • Molecule weight189.26
  • Purity≥98%
  • MDL No.MFCD24448639

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-thioxo-2,3-dihydrothiazole-4-carboxylate|CS-0095184

Structure of 56232-75-8

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General Information

  • CAS No. 56232-75-8
  • Cat. No. CS-0095184
  • Purity ≥98%
  • MDL No. MFCD24448639
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₂S₂
  • Molecular Weight 189.26
  • Synonym(s) 56232-75-8
  • SMILES O=C(C1=CSC(N1)=S)OCC

Description

Ethyl 2-thioxo-2,3-dihydrothiazole-4-carboxylate features a reactive thioxo group flanked by a dihydrothiazole scaffold, enabling efficient integration into heterocyclic syntheses. This bench-stable reagent pairs readily with nucleophiles under mild conditions, delivering functionalized thiazole derivatives with high regioselectivity.

Application

Ethyl 2-thioxo-2,3-dihydrothiazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thiazole-based scaffolds via cyclization and functionalization reactions. Its thioxo group facilitates nucleophilic addition and metal-catalyzed transformations, while the ester functionality supports orthogonal derivatization. The compound exhibits good bench stability and is compatible with standard reaction conditions, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   42.09
  • LogP   1.98239
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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