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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((2,4-dinitrophenyl)amino)propanoic acid

  • CAS No. 140430-54-2

  • Cat. No. CS-0046772
  • Purity≥95%
  • MDL No.MFCD00798650

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((2,4-dinitrophenyl)amino)propanoic acid|CS-0046772

Structure of 140430-54-2

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General Information

  • CAS No. 140430-54-2
  • Cat. No. CS-0046772
  • Purity ≥95%
  • MDL No. MFCD00798650
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₀N₄O₈
  • Molecular Weight 492.44
  • Synonym(s) Fmoc-Dap(Dnp)-OH
  • SMILES O=C(O)[C@H](CNC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((2,4-dinitrophenyl)amino)propanoic acid serves as a robust chiral building block for peptide synthesis, combining the stability of Fmoc protection with the electron-withdrawing character of the 2,4-dinitrophenyl group. Its orthogonality enables selective deprotection and facilitates efficient coupling in solid-phase workflows. The dinitrophenyl moiety enhances solubility and aids purification via chromatography, while the (S)-configuration ensures stereochemical fidelity in target molecule construction.

Safety Information

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Computational Chemistry Data

  • TPSA   173.94
  • LogP   3.9068
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   9

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