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CS-W001157 4
Total: USD 88.00

Fmoc-Aph(Hor)-OH

  • CAS No. 1253282-31-3

  • Cat. No. CS-0149874
  • Purity≥98%
  • MDL No.MFCD27923015

*For research and further manufacturing use only, not for direct human use.

Fmoc-Aph(Hor)-OH|CS-0149874

Structure of 1253282-31-3

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General Information

  • CAS No. 1253282-31-3
  • Cat. No. CS-0149874
  • Purity ≥98%
  • MDL No. MFCD27923015
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₂₆N₄O₇
  • Molecular Weight 542.54
  • Synonym(s) None
  • SMILES O=C([C@@H]1CC(NC(N1)=O)=O)NC=2C=CC(=CC2)C[C@@H](C(O)=O)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O

Description

Fmoc-Aph(Hor)-OH is a fluorophore-tagged amino acid derivative featuring a horseradish peroxidase-compatible phenylalanine analog. This bifunctional building block integrates site-specific labeling into peptide synthesis, enabling sensitive detection in immunoassays and protein-probing workflows. The Fmoc group ensures compatibility with standard solid-phase peptide synthesis protocols.

Application

Fmoc-Aph(Hor)-OH serves as a versatile building block for solid-phase peptide synthesis, enabling the incorporation of homoorotic acid—derived from the natural amino acid ornithine—into peptide architectures. Its Fmoc protection ensures compatibility with standard deprotection protocols, while the orthogonally protected side chain facilitates selective functionalization. The molecule exhibits excellent bench stability and clean coupling efficiency, making it well-suited for the synthesis of bioactive peptides and cyclic scaffolds requiring non-proteinogenic residues.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   162.93
  • LogP   2.7576
  • H_Acceptors   6
  • H_Donors   5
  • Rotatable_Bonds   8

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