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CS-W001157 4
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2-(3-((Tert-butoxycarbonyl)amino)cyclobutyl)acetic acid

  • CAS No. 1638772-19-6

  • Cat. No. CS-0447870
  • Purity≥97%
  • MDL No.MFCD28501915

*For research and further manufacturing use only, not for direct human use.

2-(3-((Tert-butoxycarbonyl)amino)cyclobutyl)acetic acid|CS-0447870

Structure of 1638772-19-6

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General Information

  • CAS No. 1638772-19-6
  • Cat. No. CS-0447870
  • Purity ≥97%
  • MDL No. MFCD28501915
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.28
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC1CC(CC(=O)O)C1

Description

This cyclobutylacetic acid derivative features a tert-butoxycarbonyl-protected amine group, enabling stable incorporation into peptide conjugates. The rigid cyclobutyl scaffold imparts conformational constraint, while the carboxylic acid side chain facilitates coupling reactions under standard conditions.

Application

2-(3-((Tert-butoxycarbonyl)amino)cyclobutyl)acetic acid serves as a versatile building block for cyclobutane-containing peptidomimetics and bioactive scaffolds. The Boc-protected amine enables orthogonal functionalization, while the acetic acid handle facilitates conjugation or further derivatization. Its stability under standard synthetic conditions and compatibility with common coupling protocols make it ideal for iterative peptide synthesis and medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.7644
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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