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Structure of 60010-03-9
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2,6-Dichloro-4-methyl-3-nitropyridine features a highly electron-deficient pyridine core flanked by two chlorine substituents and a methyl group, enabling selective coupling reactions. The nitro group at C3 enhances reactivity in nucleophilic substitution pathways. This scaffold offers robust stability under standard conditions and serves as a key intermediate in the synthesis of functionalized heterocycles for pharmaceutical and agrochemical applications.
2,6-Dichloro-4-methyl-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling selective functionalization at the 3-position via reduction or substitution. The nitro group facilitates subsequent transformations into amino derivatives, while the dichloro substituents support palladium-catalyzed cross-coupling reactions. Its methyl group provides a handle for oxidation or further derivatization. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: