3-Bromo-7-methylimidazo[1,2-a]pyridine

Name: 3-Bromo-7-methylimidazo[1,2-a]pyridine
Brand: ChemScene
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CAS No. 56051-32-2
Cat. No. CS-0038367
Purity≥96%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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3-Bromo-7-methylimidazo[1,2-a]pyridine|CS-0038367

Structure of 56051-32-2

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General Information

CAS No. 56051-32-2
Cat. No. CS-0038367
Purity ≥96%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) 3-BROMO-7-METHYL-IMIDAZO[1,2-A]PYRIDINE
SMILES CC1=CC2=NC=C(Br)N2C=C1

Description

3-Bromo-7-methylimidazo[1,2-a]pyridine is a heteroaromatic building block featuring a bromine substituent at the 3-position and a methyl group at the 7-position. This configuration enables selective functionalization in transition-metal-catalyzed coupling reactions. The compound exhibits enhanced solubility in organic solvents and stability under standard bench conditions, facilitating its integration into complex synthetic sequences for pharmaceutical and agrochemical discovery.

Application

3-Bromo-7-methylimidazo[1,2-a]pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant heterocyclic scaffolds. The bromo group facilitates efficient C–C and C–N bond formation under standard conditions, while the imidazopyridine core provides structural rigidity and favorable pharmacophoric properties. Bench-stable and compatible with diverse functional groups, it functions effectively in modular synthesis workflows for kinase inhibitors and other targeted therapeutics.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

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3-Bromo-7-methylimidazo[1,2-a]pyridine

CAS No. 56051-32-2

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