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FmocNH-PEG2-CH2CONH-PEG2-CH2COOH

  • CAS No. 560088-89-3

  • Cat. No. CS-0163267
  • Molecule weight530.57
  • Purity≥95%
  • MDL No.MFCD09752868

*For research and further manufacturing use only, not for direct human use.

FmocNH-PEG2-CH2CONH-PEG2-CH2COOH|CS-0163267

Structure of 560088-89-3

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General Information

  • CAS No. 560088-89-3
  • Cat. No. CS-0163267
  • Purity ≥95%
  • MDL No. MFCD09752868
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₃₄N₂O₉
  • Molecular Weight 530.57
  • Synonym(s) None
  • SMILES O=C(O)COCCOCCNC(COCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O

Description

FmocNH-PEG2-CH2CONH-PEG2-CH2COOH is a bifunctional PEGylated linker featuring a fluorenylmethoxy carbonyl (Fmoc) group and two terminal carboxylic acids. This structure enables efficient solid-phase synthesis and conjugation workflows, offering enhanced solubility and stability under standard bench conditions.

Application

FmocNH-PEG2-CH2CONH-PEG2-CH2COOH serves as a versatile bifunctional linker for peptide and polymer synthesis, enabling site-specific conjugation via amine and carboxyl groups. The Fmoc group provides orthogonal protection for primary amines, while the PEG2 spacers enhance solubility and reduce aggregation. Its stability under standard coupling conditions and ease of purification make it ideal for solid-phase synthesis and bioconjugation workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   141.65
  • LogP   1.7923
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   18

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