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Structure of 55873-09-1
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2-Chloro-4-hydroxypyrimidine serves as a key heterocyclic building block for medicinal chemistry and agrochemical synthesis. The chlorine at the 2-position enables efficient nucleophilic substitution, while the adjacent hydroxyl group offers a handle for derivatization. This combination facilitates direct incorporation into bioactive scaffolds with enhanced solubility and metabolic stability under standard bench conditions.
2-Chloro-4-hydroxypyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient functionalization at the C4 position via nucleophilic substitution. Its chlorine atom exhibits high reactivity toward amines, alcohols, and thiols, facilitating the construction of diverse pyrimidine derivatives. The hydroxyl group provides additional handle for derivatization or protection, enhancing synthetic flexibility. This compound demonstrates excellent bench stability and compatibility with standard reaction conditions, making it a reliable intermediate in medicinal chemistry and agrochemical development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: