Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-[1,3,4]thiadiazole-2-carboxylic acid ethyl ester

  • CAS No. 1030613-07-0

  • Cat. No. CS-W008856
  • Purity≥96%
  • MDL No.MFCD12165919

*For research and further manufacturing use only, not for direct human use.

5-Bromo-[1,3,4]thiadiazole-2-carboxylic acid ethyl ester|CS-W008856

Structure of 1030613-07-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1030613-07-0
  • Cat. No. CS-W008856
  • Purity ≥96%
  • MDL No. MFCD12165919
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BrN₂O₂S
  • Molecular Weight 237.07
  • Synonym(s) Ethyl 5-bromo-1,3,4-thiadiazole-2-carboxylate; Ethyl5-bromo-1,3,4-thiadiazole-2-carboxylate
  • SMILES O=C(C1=NN=C(Br)S1)OCC

Description

5-Bromo-[1,3,4]thiadiazole-2-carboxylic acid ethyl ester features a brominated thiadiazole core that enables direct functionalization in heterocyclic synthesis. This bench-stable, moisture-tolerant reagent integrates readily into cross-coupling and cyclization workflows, delivering access to bioactive nitrogen- and sulfur-containing scaffolds with high regiocontrol.

Application

5-Bromo-[1,3,4]thiadiazole-2-carboxylic acid ethyl ester serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromo substituent enables palladium-catalyzed cross-coupling reactions, while the ester group supports selective hydrolysis or further derivatization. This compound exhibits good bench stability, facilitates purification via standard chromatographic methods, and functions effectively in constructing bioactive [1,3,4]thiadiazole scaffolds relevant to pharmaceutical development.

Synthesis

  • Route1

    References

    • Oballa, Renata M.; Belair, Liette; Black, W. Cameron; Bleasby, Kelly; Chan, Chi Chung; Desroches, Carole; Du, Xiaobing; Gordon, Robert; Guay, Jocelyne; Guiral, Sebastien; Hafey, Michael J.; Hamelin, Emelie; Huang, Zheng; Kennedy, Brian; Lachance, Nicolas; Landry, France; Li, Chun Sing; Mancini, Joseph; Normandin, Denis; Pocai, Alessandro; Powell, David A.; Ramtohul, Yeeman K.; Skorey, Kathryn; Sorensen, Dan; Sturkenboom, Wayne; Styhler, Angela; Waddleton, Deena M.; Wang, Hao; Wong, Simon; Xu, Lijing; Zhang, Lei Journal of Medicinal Chemistry, 2011 , vol. 54, # 14 p. 5082 - 5096

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.08
  • LogP   1.4773
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1030613-07-0 sigma1030613-07-0 manufacturer1030613-07-0 price1030613-07-0 structure1030613-07-0 SDSbuy 1030613-07-01030613-07-0 supplier1030613-07-0 uses1030613-07-0 molecular weightprice of 1030613-07-01030613-07-0 chemical name formula of 1030613-07-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label