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CS-W001157 4
Total: USD 88.00

5-Bromo-2-chloropyrimidin-4-ol

  • CAS No. 844843-37-4

  • Cat. No. CS-0232731
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-chloropyrimidin-4-ol|CS-0232731

Structure of 844843-37-4

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General Information

  • CAS No. 844843-37-4
  • Cat. No. CS-0232731
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂BrClN₂O
  • Molecular Weight 209.43
  • Synonym(s) 5-bromo-2-chloropyrimidin-4(3H)-one
  • SMILES OC1=NC(Cl)=NC=C1Br

Description

5-Bromo-2-chloropyrimidin-4-ol features a halogenated pyrimidine core with complementary reactivity at C5 and C2 positions. This bench-stable compound integrates readily into heterocyclic scaffolds, enabling efficient synthesis of advanced pharmaceutical intermediates and functionalized materials under standard conditions.

Application

5-Bromo-2-chloropyrimidin-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its orthogonal halogenation pattern facilitates selective cross-coupling reactions, while the hydroxyl group provides a handle for derivatization or metal complexation. The compound exhibits good bench stability and is compatible with standard reaction conditions, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.01
  • LogP   1.5981
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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