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CS-W001157 4
Total: USD 88.00

H-Gly-Gly-Gly-OH

  • CAS No. 556-33-2

  • Cat. No. CS-W015952
  • Purity≥95%
  • MDL No.MFCD00036223

*For research and further manufacturing use only, not for direct human use.

H-Gly-Gly-Gly-OH|CS-W015952

Structure of 556-33-2

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General Information

  • CAS No. 556-33-2
  • Cat. No. CS-W015952
  • Purity ≥95%
  • MDL No. MFCD00036223
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁N₃O₄
  • Molecular Weight 189.17
  • Synonym(s) Triglycine
  • SMILES O=C(O)CNC(CNC(CN)=O)=O

Description

1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1-rac-glycerol) or LPG is a 16 carbon lipid with a phosphate headgroup and hydrocarbon tail. It is negatively charged and has a critical micelle concentration of 0.6mM.16:0 Lyso PG has been used in the synthesis of acetonide-protected pyrene PG. It may be used for the elution of cytochrome b558 in ion exchange column purification. It may also be used for the solubilisation of eubacterium proton pump protein.

Application

H-Gly-Gly-Gly-OH serves as a tripeptide building block for the synthesis of bioactive peptides and protein mimetics. Its linear sequence provides a versatile scaffold for solid-phase peptide synthesis, with excellent solubility and bench stability. The terminal amine and carboxylic acid groups enable straightforward coupling reactions, while the glycine residues offer minimal steric hindrance and high flexibility, facilitating efficient elongation in standard coupling protocols.

Synthesis

  • Route1
    • Methyl phenylalaninate|CS-0446953
      15028-44-1
    • null|null
      75719-94-7
    • ~67%
    • In-stock
      H-Gly-Gly-Gly-OH|CS-W015952
      556-33-2
    • null|null
      84814-47-1

    References

    • Carbohydrate Research, , vol. 108, p. 89 - 96
  • Route2

    References

    • Casadei, M. Antonietta; Pletcher, D. Synthesis, 1987 , # 12 p. 1118 - 1119
  • Route3

    References

    • Helvetica Chimica Acta, , vol. 63, # 4 p. 962 - 966

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   121.52
  • LogP   -2.7379
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   5

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