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CS-W001157 4
Total: USD 88.00

1-(2-Hydroxyethyl)-4-methylpiperazine

  • CAS No. 5464-12-0

  • Cat. No. CS-W003127
  • Purity≥96%
  • MDL No.MFCD03840691

*For research and further manufacturing use only, not for direct human use.

1-(2-Hydroxyethyl)-4-methylpiperazine|CS-W003127

Structure of 5464-12-0

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General Information

  • CAS No. 5464-12-0
  • Cat. No. CS-W003127
  • Purity ≥96%
  • MDL No. MFCD03840691
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆N₂O
  • Molecular Weight 144.21
  • Synonym(s) 2-(4-methylpiperazin-1-yl)ethanol
  • SMILES OCCN1CCN(CC1)C

Description

1-(2-Hydroxyethyl)-4-methylpiperazine is a bench-stable, moisture-tolerant heterocyclic amine featuring a primary hydroxyl group and a methyl-substituted piperazine core. This combination enables efficient coupling in bioconjugation workflows and enhances solubility in aqueous-organic mixtures, facilitating use in peptide derivatization and small-molecule scaffold design.

Synthesis

  • Route1
    • In-stock
      N-Methylpiperazine|CS-0009394
      109-01-3
    • null|null
      540-51-2
    • ~90%
    • In-stock
      1-(2-Hydroxyethyl)-4-methylpiperazine|CS-W003127
      5464-12-0

    References

    • WO2004/7498 A2, ; Page 29 ; WO 2004/007498 A2
  • Route2
    • 1-(2-Hydroxyethyl)piperazine Dasatinib Impurity|CS-0228904
      103-76-4
    • null|null
      50-00-0
    • ~64%
    • In-stock
      1-(2-Hydroxyethyl)-4-methylpiperazine|CS-W003127
      5464-12-0

    References

    • US2008/51397 A1, ; Page/Page column 10; 26 ;
  • Route3
    • 1-(2-Hydroxyethyl)piperazine Dasatinib Impurity|CS-0228904
      103-76-4
    • ~81%
    • In-stock
      1-(2-Hydroxyethyl)-4-methylpiperazine|CS-W003127
      5464-12-0

    References

    • US6610729 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.71
  • LogP   -0.7739
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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