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CS-W001157 4
Total: USD 88.00

(2,4-Dichlorophenyl)hydrazine hydrochloride

  • CAS No. 5446-18-4

  • Cat. No. CS-W014963
  • Purity≥95%
  • MDL No.MFCD00012929

*For research and further manufacturing use only, not for direct human use.

(2,4-Dichlorophenyl)hydrazine hydrochloride|CS-W014963

Structure of 5446-18-4

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General Information

  • CAS No. 5446-18-4
  • Cat. No. CS-W014963
  • Purity ≥95%
  • MDL No. MFCD00012929
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇Cl₃N₂
  • Molecular Weight 213.49
  • Synonym(s) 4-Bromo-3-Aminoacetophdnone
  • SMILES ClC1=CC(Cl)=C(NN)C=C1.Cl

Description

2,4-Dichlorophenylhydrazine hydrochloride was used in the synthesis of pyrazole analogues of curcumin.

Application

(2,4-Dichlorophenyl)hydrazine hydrochloride serves as a reliable building block for the synthesis of heterocyclic scaffolds, particularly in the construction of triazoles and imidazoles via cycloaddition reactions. Its bench-stable form facilitates handling and purification, while the ortho-dichloro substitution pattern enables directed functionalization and enhances metabolic stability in downstream pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      554-00-7
    • ~49%
    • In-stock
      (2,4-Dichlorophenyl)hydrazine hydrochloride|CS-W014963
      5446-18-4

    References

    • Yan, Tao; Yu, Shujing; Liu, Pengfei; Liu, Zhuo; Wang, Baolei; Xiong, Lixia; Li, Zhengming Chinese Journal of Chemistry, 2012 , vol. 30, # 4 p. 919 - 923

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.7008
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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