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Structure of 54413-93-3
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2-Iodo-5-methoxybenzoic acid features a strategically positioned iodine atom and methoxy group on the aromatic ring, enabling efficient cross-coupling reactions. The carboxylic acid functionality provides direct handle for peptide conjugation or derivatization. This bench-stable compound integrates readily into synthetic sequences requiring halogen-directed functionalization.
2-Iodo-5-methoxybenzoic acid serves as a versatile building block for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions, enabling efficient access to substituted biaryls and functionalized heterocycles. The iodide group provides high reactivity under standard coupling conditions, while the methoxy and carboxylic acid functionalities offer orthogonal handles for further derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in both academic and industrial synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: